high-resolution spatial biology

Powering high-resolution spatial biology

Discover the unknown with whole transcriptome tissue mapping

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About Curio Bioscience

We are advancing a new generation of high-precision tools for the life sciences industry. Our first product portfolio is the only continuous high-resolution, spatial whole transcriptome solution that enables unbiased gene expression mapping from fresh frozen tissue using existing DNA sequencing infrastructure.

Our spatial mapping technology powers novel insights across oncology, developmental biology, neuroscience, and more. We are led by veterans in the life science industry with a proven track record of bringing disruptive discovery technologies to market.

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Introducing Curio Seeker

The first high-resolution, whole transcriptome, spatial mapping kit

Curio Seeker Spatial Mapping Kit enables whole transcriptome, spatial mapping of fresh frozen tissue at industry-leading resolution and plugs directly into existing sequencing workflows.

The Curio Seeker tile preserves spatial information by capturing RNA on a monolayer of tightly packed, 10 μm beads.

The Power of Curio Seeker

Single-cell resolution

A tightly-packed monolayer of beads delivers a continuous view of your region of interest at 10 µm resolution.

Whole transcriptome

Whole transcriptome analysis that is not limited by predetermined targets or throughput, enabling true unbiased discovery.

Simple workflow

Leverages standard molecular biology techniques and instrumentation; no new specialized instrumentation or microscopy expertise needed.


Amenable to a wide range of tissues and species with no optimization required.

Sized to meet your needs

Conveniently offered in 3 mm x 3 mm or 10 mm x 10 mm tile sizes without sacrificing resolution.

Fast time to results

Multiple tissue samples can be prepared for sequencing in just one day.


Foundational Publications